Sequence of mGK-11, a mouse glandular kallikrein gene
نویسندگان
چکیده
منابع مشابه
Sequence of mGK-11, a mouse glandular kallikrein gene.
Like most members of the mouse glandular kallikrein gene family (for review see 1), expression of mGK-11 shows sexual dimorphism in the salivary glands, the level in males being about 30-fold greater than that in females. Nucleotide sequence from the five exons and 625 bp of the 5' flanking region was determined using the enzymatic method . The exon-intron boundaries of mGK-11 (boxed) are ident...
متن کاملSingle-chain tissue-type plasminogen activator is a substrate of mouse glandular kallikrein 24.
Leydig cells of the adult mouse testis express at a detectable level three distinct glandular (tissue) kallikrein genes: mKlk21, mKlk24, and mKlk27. Recently, the proteins encoded by these genes were characterized using active recombinant proteases, but their roles in the mouse testis remained to be determined. The present study showed that among the proteases, mK24 markedly enhanced the activi...
متن کاملMouse submandibular gland prorenin-converting enzyme is a member of glandular kallikrein family.
Mouse submandibular gland prorenin-converting enzyme (PRECE) consists of the two polypeptide chains of 17 and 10 kDa and cleaves mouse Ren-2 prorenin at a dibasic site to yield mature renin. Western blot analysis using an antiserum against this enzyme gave rise to multiple bands in mouse submandibular glands, suggesting that PRECE is a member of a protease family. Partial amino acid sequence an...
متن کاملKLK 11 ( Kallikrein - related peptidase 11 )
Three alternatively spliced variants have been described in the literature: including isoform 1, isoform 2, and isoform 3. Isoform 1 is preferentially expressed in the brain and it encodes a protein of 250 amino acids. Isoform 2 and isoform 3 are mainly expressed in the prostate. Compared to isoform 1, isoform 2 has additional 32 amino acids at the N-terminus and isoform 3 contains extra 25 ami...
متن کاملDopamine regulates expression of the glandular-type kallikrein gene at the transcriptional level in the pituitary.
A glandular-like kallikrein enzyme, a member of a well-characterized family of specific arginyl endopeptidases that may be involved in prohormone processing, has previously been shown to be present in the anterior and neurointermediate lobes of the rat pituitary. We isolated glandular-like kallikrein cDNAs from cDNA libraries prepared from these two tissues. By nucleotide sequence, restriction ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.22.10918